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Comparison of Acne Disability in patients undergoing medical, cosmetic, combination or self treatment.

Research Question & Hypothesis: (Feasible, Interesting, Novel, Ethical & Relevant) FINER

Acne disability is related to psychological morbidity. Hence cosmetic treatments either alone or in combination with medical treatment could be more effective than medical treatment alone in improving acne related disability..

Background & Justification:

Despite general acceptance of the psychosocial impact of acne, measurement of its effect on quality of life (QOL) has only begun in recent years.

Study Design

Population: New Acne patients visiting the department over a 1 year period.
Methods of recruitment (Inclusion & Exclusion Criteria)
  • A. Medical treatment group:

1. Has consulted a dermatologist or GP in last 6 months 2. Isotretinoin before 1 year period prior to presentation. 3. Oral antibiotics within 6 months 4. Topical antibiotics, Benzyl peroxide or topical retinoid use within last 6 months.

  • B. Cosmetic Treatment group:

1. Does not belong to Category A. 2. Has undergone Chemical peel, Microdermabrasion or laser treatment for acne/sequelae. 3. Use of cleansers, toners or preparations not belonging to A4.

  • C. Combination group:

B + A3 and/or A4

  • D. Self/No treatment group

All others

Inclusion Criteria:
  1. Diagnosis of Acne
  2. Willingness to participate
  3. Age between 12 to 50
  4. No other co-morbidities
Exclusion criteria
  1. Isotretinoin therapy within 1 year

Randomisation and blinding methods: N/A

Primary and secondary endpoints and outcomes: N/A


Sample size: N/A

Method of data collection:

  1. Age
  2. Sex
  3. Duration >2 years Y/N
  4. BMI
  5. Grading of acne: Global Acne Grading System or a simpler classification by Lehman
  6. Group: A/B/C/D as above
  7. Cardiff Acne disability index

Statistical analysis

  1. Age: descriptive
  2. Sex: t test (Disability score)
  3. Duration >2 years Y/N: t test (Disability score)
  4. BMI: Pearson correlation coefficient ( (Disability score)
  5. PCOS: t test ( (Disability score)
  6. Grading of acne: Pearson correlation coefficient (Disability score)
  7. Group: A/B/C/D as above: ANOVA (Disability score)

Timetable: 1 year for data collection or a suitable time frame for PG thesis.


  1. Questionnaire completed anonymously.
  2. Explain about confidentiality.
  3. Explain objective of research
  4. Written consent
  5. Ethics committee clearence



Publication plan

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About Me

I have varied research interests ranging from eHealth, Health Information Exchange, Clinical Trials and Research, Contact Dermatitis, Bioinformatics, and Cosmetic Dermatology. I have work experience in Canada as an eHealth analyst, and in Dubai and India as a Specialist Dermatologist.


Bell Raj Eapen
Hamilton, ON