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lichen striatus

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The text is the summary of recent articles on lichen striatus at 75 thresold from National Library of Medicine (NLM). This information is subject to NCBI's Disclaimer and Copyright notice.

In most cases, it is a self-limited dermatosis, but may relapse [1]. We describe the case of a 45-year-old Woman affected by a lichen striatus on her right limb resistant to topical Corticosteroid therapy [2]. Surprisingly, today, 10 years after their completion, these RCTs still remain unpublished, whereas the corresponding FDA site provides no information with regard to the researchers, the centers in which these trials were conducted, their research protocol, and the demographic data of the enrolled patients [3]. Infectious diseases were predominant in Caiabi and Kamaiur√° Indians, whereas Inflammatory skin diseases were more frequent in Ikpeng and Juruna populations [4]. The CART-EGFR Cells induced acute infusion-related toxicities such as mild chills, Fever, fatigue, vomiting and Muscle soreness, and a 9-day duration of delayed lower Fever, accompanied by escalation of IL-6 and C reactive protein (CRP), acute increase of glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase, and grade 2 lichen striatus-like skin pathological changes [5].

Immunohistochemical study showed mixed Infiltration by T-cells and B-cells around the eccrine glands [6]. Two months later, new lesions manifested as multiple erythematous, Edematous, Polycyclic Plaques [7]. A new Biopsy showed a periadnexal infiltrate, a large amount of mucin, and a thickened basement membrane [8]. A diagnosis of lichen striatus (LS) was made and the lesions completely resolved within 6 months [9]. Adult blaschkitis is a rare, relapsing Inflammatory Dermatitis that most often presents in middle age [10].

However, the clinical and histopathologic presentation of lichen striatus in adults may be similar to those of adult blaschkitis [11]. Moreover, the clinical and histopathologic overlap between the entities of blaschkitis and lichen striatus is explored, acknowledging that these entities may exist on a clinicopathologic spectrum [12]. The surface of the Atrophic Plaques was notable for prominent telangiectasia, giving an Erythematous appearance [13]. Clinically, the age of the patient, the absence of Scaling, and the presence of Atrophic Plaques and telangiectasia were in favor of ELS [14]. A punch biopsy from an Atrophic Plaque was performed, and it revealed hyperkeratosis, atrophic epidermis, basal Layer vacuolar degeneration, mild lymphocytic infiltration in the Dermis, Edema, and homogenization of collagen of the upper portion of the Dermis (Figures 3 and Figure 4) [15].

There is a considerable clinical and histological resemblance between ILVEN and linear psoriasis, lichen striatus, linear lichen planus, and invasion of Epidermal nevus by psoriasis [16]. The perineural and periappendageal Infiltrate is unusual for LA and suggestive of lichen striatus (LS) [17]. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by Inflammatory Cells [18]. Secondary changes of the epidermis and Papillary Dermis along with type, Distribution and density of Inflammatory Cells are used for the differential diagnoses of the various diseases that exhibit interface changes [19]. Lupus erythematosus, dermatomyositis, lichen planus, graft versus host disease, erythema multiforme, fixed drug Eruptions, lichen striatus, and pityriasis lichenoides are considered major interface diseases [20].

References: 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 ,

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About Me

I have varied research interests ranging from eHealth, Health Information Exchange, Clinical Trials and Research, Contact Dermatitis, Bioinformatics, and Cosmetic Dermatology. I have work experience in Canada as an eHealth analyst, and in Dubai and India as a Specialist Dermatologist.


Bell Raj Eapen
Hamilton, ON