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The text is the summary of recent articles on Painful at 75 thresold from National Library of Medicine (NLM). This information is subject to NCBI's Disclaimer and Copyright notice.

Dienogest and GnRH agonists (GnRHa) are the only treatments specifically evaluated for the treatment of adolescent endometriosis [1]. Combined Oral contraceptives have not been studied in the context of endometriosis but they are effective on dysmenorrhea [2]. The parietal operculum and adjacent posterior insula are the main recipients of spinothalamic afferents in primates [3]. The innermost operculum appears functionally associated with the posterior insula and can be segregated histologically, somatotopically and neurochemically from the more lateral S2 areas [4]. Lacking the clinical information, radiologists may inappropriately call a fluid collection or any Cystic Lesion a pseudocyst [5].

To confirm these results, we demonstrated that l-CDL controlled astrocytic-released CXCL1 by inhibiting p65/RelA activation, thus acting on the CXCR2 receptor in the spinal cord [6]. Moreover, Antifungal therapy and immunosuppressive drug interactions should be considered during treatment management [7]. GnRHa is not recommended as first line endometriosis treatment for adolescent girl because of the risk of Bone demineralization (grade B) [8]. Moreover, literature shows no interest in uterine nerve ablation in case of dysmenorrhea due to minimal and mild endometriosis [9].

References: 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 ,

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About Me

I have varied research interests ranging from eHealth, Health Information Exchange, Clinical Trials and Research, Contact Dermatitis, Bioinformatics, and Cosmetic Dermatology. I have work experience in Canada as an eHealth analyst, and in Dubai and India as a Specialist Dermatologist.


Bell Raj Eapen
Hamilton, ON