DermKnowledgeBASE: Hemangiopericytoma


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The text is the summary of recent articles on Hemangiopericytoma at 75 thresold from National Library of Medicine (NLM). This information is subject to NCBI's Disclaimer and Copyright notice.

Moreover, MGS, radiotherapy, mitotic activity ≥5/10 HPF, and Necrosis were the prognostic factors measured for DSS [1]. In conclusion, our results show that assessing the malignancy risk of SFT/HPC should not rely on one single criterion like mitotic activity [2]. The other 3 patients presented respectively neuroendocrine Carcinoma (NEC) of the palate (70-year-old woman), retroperitoneal myxofibrosarcoma (66-year-old man) and meningeal hemangiopericytoma (36-year-old woman) [3]. HPC-SFT have a high rate of local recurrence with well-known propensity for extracranial metastases [4]. Reference lists of identified articles were reviewed to detect other relevant citations [5].

There is little documentation of methods used to monitor patients with extra-cranial HPC-SFT and no clear surveillance paradigm observed [6]. None of the schwannomas or hemangiopericytomas was positive for any of both markers [7]. METHODS Histopathologically proven intracranial SFT and HPC cases treated in the period from June 1996 to September 2014 were retrospectively reviewed and analyzed [8]. Complete Surgical resection is the treatment of choice for hemangiopericytoma given their high rates of local recurrence [9]. Once hypoglycemia is diagnosed, patients often have end-stage disease [10].

There are few case reports about application of F18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in HPC [11]. A hemangiopericytoma-like growth pattern was frequently identified [12]. Histopathological diagnosis is mostly based on a "patternless pattern" on microscopic examination, which is a storiform arrangement of spindle cells combined with a "hemangiopericytoma-like appearance" and increased vascularity of the Lesion [13]. Postoperative radiotherapy is recommended to lower the Recurrent rate [14]. HPC has Malignant potential and has the capacity for Metastasis and local recurrence [15].

The observation of a sinunasal, infantile hemangiopericytoma affecting the anterior skull base and ethmoid Bone in a Female Infant is presented [16]. IMT is generally a histological diagnosis which is rarely suspected preoperatively [17]. Here, we describe a case of a 10-year-old Child which initially presented with clinical features mimicking chronic suppurative otitis media and radiological presentation of a small intracranial abscess [18].

References: 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ,

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I have varied research interests ranging from eHealth, Health Information Exchange, Clinical Trials and Research, Contact Dermatitis, Bioinformatics, and Cosmetic Dermatology. I have work experience in Canada as an eHealth analyst, and in Dubai and India as a Specialist Dermatologist.


Bell Raj Eapen
Hamilton, ON